The three major U.S. stock indexes collectively opened higher, with the Dow opening up 1.5%.bestpayingcryptogames.27%, the S & P 500 index rose 1.25%, and the Nasdaq rose 1.9%. Apple rose 7.7% as the company announced a $110 billion share repurchase planbestpayingcryptogamesAmgen rose 12%, and its mid-term trial data showed positive signs. Competitor Novo Nordisk fell 0.96%, and Lilly fell 1.7%.